
LEADING MANUFACTURER AND SOLUTION PROVIDER OF CYCLODEXTRIN MATERIALS
Shandong Binzhou Zhiyuan Biotechnology Co., Ltd. is a leading direct manufacturer specializing in cyclodextrin derivatives, inclusion compounds, and cyclodextrin-based reagents, located in Binzhou, Shandong, China.
Founded in 2010, the company covers an area of 30,000 square meters, with a 10,000-square-meter modern facility and fixed assets totaling 200 million RMB, including advanced inspection instruments worth over 20 million RMB. We have established a GMP-compliant clean production workshop for pharmaceutical excipients, a large-scale medical-grade storage warehouse, and a fully equipped R&D, quality inspection, and professional production team.
Zhiyuan offers five main series of products-Natural Cyclodextrins, Cyclodextrin Derivatives, Cyclodextrin Reagents, Cyclodextrin Complexes, and Cyclodextrin Polymers-with over 50 types of cyclodextrins. These are widely used in pharmaceuticals, food, cosmetics, fragrances, agriculture, and other industries.
Key products such as Hydroxypropyl Betadex, Betadex Sulfobutyl Ether Sodium, and Hydroxypropyl Gamma-Cyclodextrin have been approved by the U.S. FDA and hold valid DMF registrations.
All production processes strictly adhere to GMP guidelines and meet multiple international standards, including CP, USP, and EP.
We sincerely look forward to working with you to explore the unlimited possibilities of cyclodextrin applications.
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30000+Square Meters Built -
100+Enterprise employees -
1000+Clients -
70+Cyclodextrin Materials
Mission&Vision
Enterprise Mission: Explore the infinite application of cyclodextrin in human activities .
Enterprise Vision: To be the global leader in the field of cyclodextrin.


Core Values
Zhiyuan has 5 series (Nature Cyclodextrins, Cyclodextrin Derivatives, Cyclodextrin Reagents, Cyclodextrin Complexes, Cyclodextrin Polymers ) of more than 50 kinds of cyclodextrins which have been widely used in pharmaceutics, foods, cosmetics, fragrances, pesticides and other industrial production. Hydroxypropyl Betadex, Betadex Sulfobutyl Ether Sodium and Hydroxypropy Gamma Cyclodextrin have approved by the U.S. FDA and obtained DMF registration. The production strictly follows GMP and meets the multiple standards such as CP, USP, EP. Sincerely looking forward to exploring infinite applications with you in the cyclodextrin field.

