CAS 128446-34-4 (2-Hydroxypropyl)-γ-Cyclodextrin
Quick Details
|
Name: |
CAS 128446-34-4 (2-Hydroxypropyl)-γ-Cyclodextrin |
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CAS Number: |
128446-34-4 |
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Abbreviation: |
HPGCD |
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Cyclodextrin type: |
Randomly substituted cyclodextrins, neutral |
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Quality: |
Research grade，Technical Grade |
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Availability |
In stock |
Product Introduction
CAS 128446-34-4 (2-Hydroxypropyl)-γ-Cyclodextrin belongs to the class of cyclodextrin derivatives, which exhibit a greater extent of solubility in water compared to their parent compounds. It is widely used in parenteral formulations and solid dosage forms to aid in the improvement of their stability, dissolution, bioavailability, etc.
Chemical and Physical descripton
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Average Molecular Formula |
C48H80-nO40 · (C3H7O)n |
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Average Formula Weight |
1297.2 + n·(58.1) |
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Appearance (Colour) |
White to off white |
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Melting Point |
>240°C (dec.) |
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Solubility |
Water: > 50g； |
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Applications |
2-HYDROXYPROPYL .GAMMA.-CYCLODEXTRIN is used in the solubilization of macromolecules and in cell culture applications. Similar to beta Cyclodextrin ,but it can work with larger molecules. |
Specification
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ITEMS |
CRITERIA |
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Appearance |
White or almost white powder;Odorless, slightly sweet;Freely soluble in water,soluble in ethanol,almost insoluble in acetone . |
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Water solution pH |
pH5.0～8.5 |
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Light-absorbing impurities |
max. 0.5 (230 – 660 nm) |
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Water |
≤10.0％ |
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Alpha Cyclodextrin |
≤1.5% |
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Residue on ignition |
≤0.2％ |
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Heavy Metal |
≤10ppm |
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Propylene glycol |
≤0.5％ |
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Assay |
≥98% |
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Hydroxypropoxyl content |
17.5%～29.1% |
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The total aerobic microbial count |
≤103cfu/g |
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The total combined moulds and yeasts count |
≤102cfu/g |
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Escherichia coli |
Absence |
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Bacterial Endotoxins Test |
According to preparation needs <0.01EU/mg |
Application
CAS 128446-34-4 (2-Hydroxypropyl)-γ-Cyclodextrin only for reagent and laboratory purposes, not for human use；
Laboratory chemicals, manufacture of substances,solubilizer, chiral selector；
Solvent Enhancer, Embedding Agent, Analytical Reagent；
Packing & Storage
On-demand pack size is available without surcharge.
This Product is available in multi-kilograms pack size, such as: 1kg,5kg,10kg
★Internal packing: PE bag and aluminum foil bag
★Outer packing: carton or drum.
★Storage:Preserve well-closed containers protect from moisture.
Shipping Information
★Tariff No.：3505100000
Safety Features
Description of first aid measures for (2-Hydroxypropyl)-g-cyclodextrin
General advice
1
If inhaled
Remove to fresh air and monitor breathing. If breathing becomes difficult, give oxygen. If breathing stops, give artificial respiration. Consult a doctor.
2
In case of skin contact
Immediately wash skin with copious amounts of soap and water for at least 15 minutes. Remove contaminated clothing and shoes and wash before reuse. Consult a doctor.
3
In case of eye contact
Flush with copious amounts of water for at least 15 minutes. Consult a doctor.
4
If swallowed
Rinse mouth with water. Do not induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconscious person. Consult a doctor.
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