Piroxicam Beta Cyclodextrin
Quick Details
|
Name |
Piroxicam beta cyclodextrin |
|
CAS No. |
96684-39-8 |
|
Molecular Formula |
C42 H70 O35 . x C15 H13 N3 O4 S |
|
Color of Solution |
0.50g/100ml water solution is light yellow |
|
Content of Piroxicam |
9.5%-11.5% |
|
Package |
10kg/drum,25kg/drum |
|
Water solution pH |
pH5.0~8.0 |
|
Storage |
Preserve in well-closed containers. |
Product Introduction
Piroxicam belongs to a class of non-steroidal anti-inflammatory drugs with anti-inflammatory effects. However, it is poorly soluble in water and is slowly absorbed. When taken orally, it can lead to gastrointestinal bleeding and ulcers. Muscle injections of the drug may cause pain at the injection site and mild tissue necrosis. By preparing piroxicam as a piroxicam-beta-cyclodextrin inclusion compound, the dissolution rate of the drug can be increased, reducing gastrointestinal irritation. The oral analgesic Xi Tong (Cycladol), which contains piroxicam-beta-cyclodextrin complex, represents a successful application of this entrapped cyclodextrin complex.
Application advantages
Piroxicam-beta-cyclodextrin (also known as Inflammatory Pain Relief Cyclodextrin) represents a new technology. Our company has developed a unique process involving the combination of pharmaceutical-grade piroxicam and pharmaceutical-grade beta-cyclodextrin to form inclusion complexes. Compared to piroxicam monomers, the complex exhibits reduced odor, increased stability, and a more consistent drug release rate.
Production process
1
Piroxicam-Beta-Cyclodextrin is made by enwrapping medical piroxicam and medical beta-cyclodextrin in a certain inverse proportion with a unique art.
2
This inclusion compound has less odor, more stability and more stable medicine releasing speed than the single piroxicam.
3
Piroxicam-Beta-Cyclodextrin is mainly used in anti-inflammatory analgesic drugs. It is more useful in the medical.
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